A.) Based on your data and observations, what are some of the differences betwee

Question

A.)    Based on your data and observations, what are some of the differences between normal cells and cancer cells?

B.)    When studying cell division in tissue samples, scientists often calculate a mitotic index, which is the ratio of dividing cells to the total number of cells in the sample. Which type of tissue had a higher mitotic index, normal tissue or cancerous tissue? Explain.

C.)    c. Different types of normal tissues in the human body have different mitotic indices. Which normal cell tissue had the highest mitotic index? Why did this cell type would have the highest mitotic index?

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G. Percentage of Percentage of F. Total number of cells cells dividing cells at rest Mitotic index: (GVH) A. Interphase B. Prophase Metaphase D. Anaphase E. Telophase (A+B+C+D+E) (B+C+D+EMF .05 OR 5% 95 OR 95% 0.05 OR 5% Cancerous .20R 20% OR 80% Normal stomach 20R 20% SOR 80% 0.2SOR 25%. 14 2 1 1 2 20 cncerous Stomach 30R 30% 7 OR 70% 0.43 OR 43% .05 OR 59% ,95 OR 95% 0.05 OR No mal ovary AOR 40% J60R 60% .617 OR 67% Cancerous ovary A.) Based on your data and observations, what are some of the differences between normal cells and cancer cells? B.) When studying cell division in tissue samples, scientists often calculate a mitotic index, which is the ratio of dividing cells to the total number of cells in the sample Which type of tissue had a higher mitotic index, normal tissue or cancerous tissue? Explain C) C. Different types of normal tissues in the human body have different mitotic indices. Which normal cell tissue had the highest mitotic index? Why did this cell type would have the highest mitotic index?

Explanation / Answer

A. The major takeaway from the observations is that a large number of cancer cells, unlike normal cells, keep dividing. This happens even in the absence of external cell division signals. Normal cells approach a limit called the Hayflick limit for the dividing cells, while the cancer cells ignore this limit.

B. A cancerous tissue will have a higher mitotic index than the same type of normal tissue, as they are able to divide without external signalling directing it to do so, and ignores damage to DNA while dividing by skipping various checkpoints.

C. The highest mitotic index of normal skin cells in the human cells are of the skin cells, epithelial lining of the gut and various internal cavities. This is because these cells are damaged fast due to exposure and have to be replaced soon to avoid risk of infection.

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