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Given the following: - Excess acetoacetyl CoA is available - All the acetyl CoA

ID: 165282 • Letter: G

Question

Given the following:

- Excess acetoacetyl CoA is available

- All the acetyl CoA made in the beta-oxidation of palmitate goes directly for cholesterol biosynthesis

- Each acetyl CoA is used sequentially

- All of the steps of cholesterol biosynthesis occur sequentially and not in parallel

- The 7th carbon on Palmitate CoA is radiolabeled

From the list below, select the 1st material that appears with the radiolabel in the cholesterol biosynthetic pathway.

A. Dimethylallyl Pyrophosphate

B. Geranyl Pyrophosphate

C. Farnesyl Pyrophosphate

D. Squalene

E. Gerbyne

Explanation / Answer

First radio label appears in Dimethylallyl pyrophosphate which is prepaired from 5-pyrophasphomevalonate

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