Question
Last year. Jackie bought a wild mustang on a whim while she was visiting friends in Utah. After hearing that there is a population explosion of these wild or "feral" horses, she knew her family would be the perfect adoptive family, since they have several acres of land and also some unoccupied beams on her property. the horse she got had been neutered a while back, in an attempt at population control. the horse had a pleasant temperament and the training went well in all respects except one. He reacted violently to being tied in confined places. Jackie recently found out after doing some research, that when the surgery to neuter him was performed, the veterinarian doing the surgery used a drug that acts as a nicotinic blocking agent, commonly called "six" in hospital settings. Her research revealed stories about people going through surgery involving similar drugs, and while unable to move at all, felt everything (pain included) that was being done to them. A toxin similar to this drug is called curare. Curare, which comes from the bark of a tree in South America was used by South American Indians on their arrowheads or blow darts when they went hunting. Curare also acts as a nicotinic blocking agent and so causes the same paralytic effects. Where are, the receptors affected by "six" found and which neurotransmitter binds to them? What is the result of the normal activation of these receptors?
Explanation / Answer
15a)Sux attaches to the nicotine receptor at the neuromuscular junction in the central nervous system .The neuro receptor binds to them is Acetylcholine ... The neurotransmitter molecules bind to receptors on the postsynaptic membrane. There are in the brain.......
b)The result of normal activation of these receptors cause Postsynaptic defect of CMS and often result in abnormalities in nicotinic acetylcholine receptors.. the entry of sodium ions, resulting in the depolarization of the effector cell and therefore causes temporary paralysis.................
