BIOL2416-41480: Genetics ourse Home Chapter 19: Epigenetics Chapter 19-Question

Question

BIOL2416-41480: Genetics ourse Home Chapter 19: Epigenetics Chapter 19-Question 15 Part A Which of the following statements is most true regarding X-inactivation? 0 X-chromosomes that remain active are called Barr bodies. X-inactivation results in repressing the expression of approximately 75% of the genes on the X-chromosome. X-inactivation is more common in males than females. X-inactivation is caused primanly by the expression of several small noncoding RNAs (sncRNA). when a cell divides, the inactive X ( romosome remains inactive in the newly formed cell. Submit

Explanation / Answer

d) is true

X inactivation is done by small non coading rna known as XIST rna.

The inactive X chromosome appears as darkly stained body known as barr body. Barr body is most common in females as they have two X chromosomes and hence two set of genes, so in order to equilibriate it with the male which has only one X chromosome, one X chromosome out of 2 is inactivated and this is a random process. During division both X chromosome is normal neither is inactivated but after zygotic stage barr body formation takes place.

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