In chemical signaling, a cell may target itself (autocrine signaling), a cell co

Question

In chemical signaling, a cell may target itself (autocrine signaling), a cell connected by gap junctions,a nearby cell (paracrine signaling), or a distant cell (endocrine signaling). Paracrine signaling acts on nearby cells,endocrine signaling uses the circulatory system to transport ligands, and autocrine signaling acts on the signaling cell.Signaling via gap junctions involves signaling molecules moving directly between adjacent cells.

As I understand it, the cell secretes a ligand that binds it's own receptor to induce a downstream effect. I'm just wondering why the cell can't just internally modulate the downstream effect instead of secreting something that binds externally. It seems like extra work for the cell. Any opinions??

Explanation / Answer

Each cell based on the organ it presents have different functions that is cell present in heart requires some set of proteins to work where as cell in liver needsome other type of proteins to work.

Each cell in the body contains the same amount of DNA and chromosomes and genes. So that each cell can produce any protein in the total DNA.

So the controlling system is present in the brain which should be activated in which cells which helps the cells from preventing doing extra work.

If an external ligand binds and directs produce a proteins the cell produce only that protein necessary for the organ it presents in to work properly.

So that it cannot analyze the whole DNA and produces all proteins it is waste full .

If a cell can produce all proteins then the specific activity of the organ is lost.

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