It has recently become possible to \"weigh\" DNA molecules by measuring the infl
ID: 1483844 • Letter: I
Question
It has recently become possible to "weigh" DNA molecules by measuring the influence of their mass on a nano-oscillator. Figure shows a thin rectangular cantilever etched out of silicon (density 2300 kg/m3) with a small gold dot at the end. If pulled down and released, the end of the cantilever vibrates with simple harmonic motion, moving up and down like a diving board after a jump. When bathed with DNA molecules whose ends have been modified to bind with gold, one or more molecules may attach to the gold dot. The addition of their mass causes a very slight-but measurable-decrease in the oscillation frequency. A vibrating cantilever of mass M can be modeled as a block of mass 13M attached to a spring. (The factor of 13 arises from the moment of inertia of a bar pivoted at one end.) Neither the mass nor the spring constant can be determined very accurately-perhaps to only two significant figures-but the oscillation frequency can be measured with very high precision simply by counting the oscillations. In one experiment, the cantilever was initially vibrating at exactly 11 MHz . Attachment of a DNA molecule caused the frequency to decrease by 40 Hz .
Part A
What was the mass of the DNA?
Express your answer using two significant figures.
It has recently become possible to "weigh" DNA molecules by measuring the influence of their mass on a nano-oscillator. Figure shows a thin rectangular cantilever etched out of silicon (density 2300 kg/m3) with a small gold dot at the end. If pulled down and released, the end of the cantilever vibrates with simple harmonic motion, moving up and down like a diving board after a jump. When bathed with DNA molecules whose ends have been modified to bind with gold, one or more molecules may attach to the gold dot. The addition of their mass causes a very slight-but measurable-decrease in the oscillation frequency. A vibrating cantilever of mass M can be modeled as a block of mass 13M attached to a spring. (The factor of 13 arises from the moment of inertia of a bar pivoted at one end.) Neither the mass nor the spring constant can be determined very accurately-perhaps to only two significant figures-but the oscillation frequency can be measured with very high precision simply by counting the oscillations. In one experiment, the cantilever was initially vibrating at exactly 11 MHz . Attachment of a DNA molecule caused the frequency to decrease by 40 Hz .
Part A
What was the mass of the DNA?
Express your answer using two significant figures.
mDNA =Explanation / Answer
this system is acting like a compound pendulum whose time period can be find as -
T = 2pi [I/mgh]0.5
so ratio of the frequency can be find as -
f1/f2 = [(m1/m2)*(I2/I1)]0.5
11*106/40 = [(m1/m2)*(I2/I1)]0.5
11*106/40 = [(m/m+M)*(13m+M/13m)]0.5
11*106/40 = [(m/m+M)*(13m+M/13m)]
7.56*1010 = 13 m2 + mM/[13m2 + 13mM]
LET 7.56*1010 = K
13 m2K + 13mMK = 13 m2 + mM
13 mK + 13MK = 13 m + M
13m [k - 1] = M [1 - 13 k]
M = 13m[k -1]/[1 - 13 k]
M = m
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