How many \"cross-overs\" are required to determine the order of 3 genes? A. Sing

Question

How many "cross-overs" are required to determine the order of 3 genes? A. Single B. Double c. More than 10 E. None () In a single, how many remain parental (non-crossover)? A. 1 B. 2 C. 3 D. 4 Identify for "3-point mapping": A. parents for all 3 genes B. Phenotype class must reflect genotype of parents C. sufficient number of offspring must be produced D. All of the above What is the basis of 'mapping" genes? A. Crossing over B. Synopsis C. Linkage D. Centromere absence What is produced in "greater" number in F2 phenotypes? A. non-crossover B. Single crossover(SCO) C. Double crossover (DCO) D. All the above What is produced in "lowest" number in F2 phenotypes? A. non-crossover B. Single crossover(SCO) C. Double crossover (DCO) D. All the above Calculate "coefficient of coincidence (C) if number of "observed" DCO is 3 an "expected is 6: A. 0.5 B. 2 C. 3 D. 9 interference (I) in the equation above: 0.5 B. 2 C. 3 D. 9 A " complete" interference occurs when: A. No DCO B. Observed DCO fewer than expected C. Observed DCO more than expected D. All of the above "Cystic fibrosis" is a good example of: A. Short repetitive sequence (microsatellite) Which of the following transduction methods target ONLY certain genes to be A. Regular B. Generalized C. Specialized d. None of the above By what structure factor are transferred from one to anther bacterium during conjugation? A. Pseudopodium B. Tentacles C. D. Plus A mutant bacterium for a particular nutrient cannot grow in a medium that lacks that nutrient is known as: A. Autotroph B. Heterotroph C. Auxotroph D. All of the above The bacterial cells that can picked naked DNA from outside (extracellular) during transformation are known as? A. Recombinant cell B. Genetically engineered cells D. Helper cell If the plasmid DNA "F factor ()" incorporated into the bacterial DNA, it is known as: A. An hfr (High frequency of recombination) cell B. F^+ cell C. F cell D. F cell

Explanation / Answer

Answer:

1). C. Linkage

Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.

2). A. 1 percent recombination between two genes on a chromosome

Map units of distance = % of recombination frequency

3). B. Double

Single cross over and double cross over are both required to determine the order of 3 genes.

4). B. 2

In a single crossover, two chromatids will be new due to crossover and the remaing two chromatids will be parental chromatids.

5). D. All of the above

For test crosses of three-point mapping, three criteria must be met:

i. Genotype of organism producing the crossover gametes are heterozygous at all loci in question
ii. Observe phenotypes of resulting offspring since gametes and genotypes can't be observed directly
iii. Sufficient # of offspring must be produced (high baby # in Drosophila).

6). C. Linkage

Linkage analysis is the basis of genetic mapping

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