Use the Oxygen-Hb Dissociation Curve (aka O 2 -Hb Binding Curve) to answer the f
ID: 100106 • Letter: U
Question
Use the Oxygen-Hb Dissociation Curve (aka O2-Hb Binding Curve) to answer the following questions:
If the blood pH is stable at 7.4, then:
What is the percent saturation of Hb (hemoglobin) in the blood as it leaves the lungs?
What is the percent saturation of Hb in the blood as it leaves the tissues?
If the blood pH is stable but slightly alkaline at 7.6, then:
What is the percent saturation of Hb (hemoglobin) in the blood as it leaves the lungs?
What is the percent saturation of Hb in the blood as it leaves the tissues?
What percentage of hemoglobin unloaded oxygen as it passed through the tissues? In other words, what is the difference in Hb-saturation before vs. after the blood passed through the tissues?
At pH 7.4?
At pH 7.6?
EFFECTS OF PH 100 8 80 7.6 80 7.4 7.2 o 60 40 20 0 20 40 60 80 100 Po2 (mm Hg)Explanation / Answer
Answer:
If the blood pH is stable at 7.4, then:
1) What is the percent saturation of Hb (hemoglobin) in the blood as it leaves the lungs? 97-100% (when the blood leaves the lungs it is saturated completely or 100% with oxygen, hemoglobin can bind up to four Oxygen molecules)
What is the percent saturation of Hb in the blood as it leaves the tissues? 75% (When blood leaves the tissue it is around 75% saturated as it releases some oxygen)
If the blood pH is stable but slightly alkaline at 7.6, then: (The curve shifts slightly to the left when pH is 7.6)
What is the percent saturation of Hb (hemoglobin) in the blood as it leaves the lungs? 100% (When blood leaves the lungs it is around 100% saturated in alkaline conditions)
What is the percent saturation of Hb in the blood as it leaves the tissues? 80% (When blood leaves the tissue it is around 80% saturated in alkaline conditions)
What percentage of hemoglobin unloaded oxygen as it passed through the tissues? In other words, what is the difference in Hb-saturation before vs. after the blood passed through the tissues? 20% is unloaded as it is passed through lungs.
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