Use the Oxygen-Hb Dissociation Curve (aka O 2 -Hb Binding Curve) shown below to

Question

Use the Oxygen-Hb Dissociation Curve (aka O2-Hb Binding Curve) shown below to answer the following questions (assume typical lung and tissue partial pressures of oxygen – see your lecture videos for what values to use):

2 points. Normal conditions (no CO present):

Graph Interpretation - Approximately what percent of Hb is saturated with oxygen after exchange with the lungs?

Graph Interpretation - Approximately what percent of Hb is saturated with oxygen after exchange with the tissues?

Calculation - What is the difference of Hb % saturation before vs after exchange with the tissues? In other words, how much of the hemoglobin unloaded at least some oxygen (e.g. is no longer fully saturated) when it passed through the tissues?

Explanation / Answer

As it is not clear that person is asking for a numeric figure answer but question explnation says that to transfer oxygen our body required a medium which is done by hemoglobin which is an protein.Hemoglobin is an iron contatinig protein which work as oxygen carrier,this oxygen-hemoglobin binding bond is quite strong but as graph is also showing more percent rate of carbo monoxide this is beacuse carbo monoxide has double ratio of binding capacity with hemoglobin, if environment has high carbon monoxide concentration then hemoglobin will bind more easily to carbon monoxide and it will carry carbon monoxide in the body and if level of it increase it can also lead to death.

So there is 40% of transfer rate of oxygen between body and tissue.

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