PHS 2201-10417 Final Exam BID: Format Se Questions (A: True; B: False) True or (
ID: 994938 • Letter: P
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PHS 2201-10417 Final Exam BID: Format Se Questions (A: True; B: False) True or (2 pointquestion) Hydrolysis of ATP is required for the enzyme activity of Topoisomerase II. 22. Watson and Crick proposed DNA double helix model in 1950. 23. tRNA , mRNA, and rRNA are all made in the nucleus of eukaryotic cells. Hydrogen bond is involved in the DNA-histone interaction. 25 . Grapefruit juice can form the complex with statins and thus repress action of the statins. 26 . Deficiency of vitamin B9 can lead to anemia . 27. will consume -THFgenerate Methionine cycle N5methylene , but S-adenosylmethionine. 28 . Nitric oxide synthetase catalyzes a deamination reaction. 29. Leucine and Isoleucine are both glucogenic.T 30. During the translation, empty tRNA will be eventually released from E site in ribosome. 31. Phosphodiester bond is located between nucleosides in both DNA and RNA. 32 . Bacterial 80s ribosome can dissociate into 30s and 50s. 33 . AUG is a start codon during the translation. 34. During eating (or in fed state, the concentration of fatty acids in the blood is high because of absorption of dietary lipids. Fal 35. DNA polymerase and DNA ligase are both required for both mismatch repair and excision repair. 36. Silence RNA is involved in DNA transcription. 37. The DNA primers that are important for DNA replication in bacteria are synthesized by DNA polymerases. 38 . Deficiency of Phenylalanine can cause the absence of skin color. 39 . Action of Topoisomerase I can, but Topoisomerae II cannot generate positive supercoils. 40. Citrate activates, but AMP represses acetyl-CoA carboxylase. 41 . HMG-CoA generated in the hepatocyte mitochondria can be used for cholesterol biosynthesis. 42. The backbone of sphingolipids is Serine. 43. Both fumarase and enoyl-CoA hydratase use the same mechanism to produce chiral product.Explanation / Answer
As we are only allowed to answer to 1 question per Q&A I will answer only the 21.
TRUE. The enzyme activty use the hydrolysis of ATP, unlike Type I topoisomerase. The hIdrolysis of ATP release of an inorganic phosphate leads to the cleavage of the G-segment in the strand passage mechanism of type II topoisomerases
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