1. Choose one out of paracrine signalling, endocrine signalling, autocrine signa

Question

1.Choose one out of paracrine signalling, endocrine signalling, autocrine signalling and direct signalling and describe briefly the process by which this occurs. Pick a representative signal molecule from the pathway you have chosen and indicate its function, the type of cell in which it is made and the specific manner in which it acts as a signalling molecule, including the receptor that it binds to.
2.Open the KEGG PATHWAY Database homepage http://www.genome.jp/kegg/pathway.html

On this page, you can browse various types of pathways, including metabolic and signalling pathways or you can search for terms and find the associated pathways.

Using the search box, search for the molecule you have discussed above by entering its name.KEGG may give you the choice between several pathways, choose one of these and click on the link under the heading ‘entry’. (this will read something like map01578)Read the description of the pathway and write down its name then click on the image of the map.If possible copy the image of the map and insert it into your written assignment, if this does not work for you provide a URL so that the page can easily be accessed.
3.Try to identify your chosen molecule on the map and make a note of the number and names of other molecules it directly interacts with in this pathway. If you are unable to identify your molecule of choice see if you can find its receptor, which you identified earlier in this assignment.Click on the shape that contains your molecule of interest (or its receptor) (this will redirect you to a page that lists the signalling pathways in which that molecule is involved and any diseases associated with it)Take a note of the names of at least three other pathways indicated on this page and comment on whether your molecule is linked with any diseases. (If there is no disease association there will be no entry in the table)

Explanation / Answer

Ans-1- endocrine signalling- it is used to communicate the distant cell to perform some action. Endocrine system is responsible for this signalling. Various gland are present to secrete some chemicals which are called hormones.

Hormones acts as messenger which are used our body to give command to some part of our body to perform some action. There are various types of hormones

One of the types of hormones include peptide hormones. These binds to specific receptor present over target cell membrane. The mainly binds to G protein coupled receptor.

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