1.Assume you have isolated an unknown virus. It is a single-stranded RNA, envelo
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Question
1.Assume you have isolated an unknown virus. It is a single-stranded RNA, enveloped virus. To which group does it most likely belong?
a. Herpesvirus
b. Picornavirus
c. Retrovirus
d. Togavirus
e. Papovavirus
2. To which group does a small, nonenveloped single-stranded RNA virus most likely belong?
a. Herpesvirus
b. Picornavirus
c. Retrovirus
d. Togavirus
e. Papovavirus
3. Viruses that have reverse transcriptase are in the
a. Retroviridae and Picornaviridae.
b. Herpesviridae and Retroviridae.
c. Hepadnaviridae and Retroviridae.
d. Bacteriophage families.
e. Influenzavirus.
4. Approximately how many virus particles, 333nm each, could fit along a 1-millimeter line?
a. 3
b. 30
c. 300
d. 3,000
e. 30,000
5.Which one of the following steps does NOT occur during multiplication of a picornavirus?
a. Synthesis of + strands of RNA
b. Synthesis of - strands of RNA
c. Synthesis of viral proteins
d. Synthesis of DNA
e. None of the above
6. All of the following viruses can cause cancer in animals EXCEPT?
a. Hepatitis C
b. Hepatitis B
c. Oncovirus
d. Mastadenovirus
e. Herpesvirus 4 (Epstein-Barr virus)
7.This family of viruses cause warts, polyomas, and vacuolation.
a. Poxviridae
b. Caliciviridae
c. Filoviridae
d. Reoviridae
e. Papovaviridae
8.These viruses are responsible for fever blisters (cold sores) and can be transmitted via oral and genital routes.
a. Roseolavirus (HHV-6) & Kaposi’s sarcoma virus (HHV-8)
b. Hepatitis A & Hepatitis E viruses
c. Flavivirus & Hepatitis C virus
d. Herpes Simplex viruses 1 and 2
9. Human Herpesvirus 4 is unusual because:
a. it is transmitted in body secretions such as breast milk and semen.
b. it is transmitted by an arthropod vector (tick).
c. it is responsible for causing at least two different diseases (Burkitt’s lymphoma & infectious mononucleosis).
d. it causes cells to enlarge and acquire inclusion bodies.
10. What do yellow fever, dengue, eastern & western equine encephalitis, and West Nile virus encephalitis all have in common?
a. They are all viral diseases of humans that are transmitted by ticks.
b. They are all viral diseases of humans that are transmitted by mosquitoes.
c. They are all viral diseases of humans that are considered to be new & emerging (EIDs).
d. All of the above.
e. None of the above.
11.Viruses like Marburg and Ebola cause fever and profuse bleeding from all orifices in humans. What is the term used to describe diseases caused by these viruses?
a. Arboviral Encephalitis
b. Cytomegaly
c. Cold sore / fever blister
d. Viral Variola
e. Viral Hemorrhagic Fevers
12.The Lyssavirus, family Rhabdoviridae, is the causitve agent of rabies. Which of the following is true about this virus?
a. It is unique in that its incubation period is usually long enough to allow immunity to develop from post-exposure vaccination.
b. Mutant strains develop rapidly because it is a single-stranded RNA virus with no proofreading capability.
c. It is usually transmitted through the bite of an infected animal.
d. The virus proliferates in the peripheral nervous system and moves fatally to the central nervous system.
e. All of the above.
13.What virus causes the majority of cases of the common cold?
a. Coronavirus
b. Influenzavirus
c. Rubivirus
d. Rhinovirus
14.What is the virus that is frequently in the news, is associated with large gatherings that have food, causes acute gastroenteritis with vomiting and/or diarrhea, and is transmitted via a fecal-oral route from food, water, or vomitus aerosols?
a. Norovirus
b. Hepatitis B
c. Rubulavirus (mumps)
d. Coronavirus (severe acute respiratory syndrome – SARS virus)
15.Why are the retroviruses unique among RNA viruses?
a. They copy their RNA genome into double-stranded DNA using reverse transcriptase.
b. Their genome consists of 8 different (-) strands of RNA.
c. They use viral integrase to incorporate their newly made double-stranded DNA into the host cell chromosome.
d. Both A and B.
e. Both A and C.
Explanation / Answer
1. D - Togavirus is the only ss+ enveloped virus on the list 2. B - picorna = pico + rna where pico means "small" (very small), & rna = RNA 3. C 4. D - 1 nm = 1,000,000 mm 1000000nm/333nm = approx 3000 units 5. 6. D - 7. E - papavoviridae include human papillomavirus, the cause of warts 8. D 9. C 10. B 11. E 12. 13. D 14. A 15. E
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