1. Based on your understanding of sea urchin gastrulation, and the morphology of
ID: 98279 • Letter: 1
Question
1. Based on your understanding of sea urchin gastrulation, and the morphology of sea urchin and fruit fly embryos during gastrulation, would you expect the ventral invagination event to require an epithelial-to-mesenchymal transition? Why or why not? Please justify your answer.
2. You are trying to establish mosquitoes as a model organism for studying insect development in order to design more effective pesticides. After sequencing the genome of Culiseta longiareolata, you uncover a gene that has a 54% sequence similarity to the bicoid gene in the fruit fly Drosophila melanogaster. As a result, you’ve named it bicoid-like. To begin determining if the bicoid-like gene in the mosquito is similar to its homolog in the fruit fly, you’ve decided to first test if the bicoid-like gene is a morphogen. How would you test whether bicoid-like is morphogen? In your response, be sure to include which technique(s) you would use and your predicted result(s)
These questions came from a Developmental Biology college course. Please explain why you chose your answer.
Explanation / Answer
1. Yes ventral invagination event requires an epithelial to mesenchymal transition in sea urchin.
2. It is required epithelial cell to mesenchymal stem cells. which are multi-potent stem cells.
3. The multipotent stem cells that helps to differentiate into other variety of cells.
4. Mesenchymal cells helps in the formation of neural tube and mesoderm.
5. In the case of Drosophila this transition is required to for the formation of body plan and differentiation of multiple tissues and organs.
6. Bicoid gene is morphogen. It helps in the process of development especially during pattern formation.
7. The techniques such as Planar multicellular system, Pair correlation function and Quadrat histogram are used to determine morphonogenic process.
8. This investigate of cell differentiation related to intra and inter cellular signaling pathway.
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