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You are interested in studying heart function, therefore you have been culturing

ID: 98218 • Letter: Y

Question

You are interested in studying heart function, therefore you have been culturing cardiomyocytes in the lab. Cardiomyocytes are the muscle cells of the heart, and you can visualize them contracting in a petri dish.

You design siRNAs against several proteins which you think will be imprtant in producing a muscle contraction, and you introduce the siRNAs individually into the cardiomyocytes, then observe their ability to contract. Please see picture for data.

A. What can you conclude about the function of Gene A?

B. What can you conclude abou the function of Gene B?

C. What can you conclude about the function of Gene C?

D. Your colleague has doubts about your results for Gene A. She suggests that the phenotype observed in sample 2 may not be due to the siRNA targeting Gene A. Explain why she might be correct.

Bookmarks People Window Help om/drive/toiders/OBXITbNtdizEsUXhMUG9BdGZhcjO QUESTION 6 You are interested in studying heart function, therefore you have been culturing cardiomyocytes in the lab. Cardiomyocytes are the muscle cells of the heart, and you can visualize them contracting in a petri dish, You design siRNAs against several proteins which you think will be important in producing a muscle contraction, and you introduce the siRNAs individually into the cardiomyocytes, then observe their ability to contract. You record the following data: Sample # Gene targeted by siRNA None Gene A Gene B Gene C phenotype contracts every 1 second Cells remain contracted Cells remain relaxed Cells contract every 0.5 seconds A) What can you conclude about the function of Gene A? D) What can you conclude about the function of Gene B c) Your colleague has doubts about your results for gene A. She suggests that the phenotype observed in sample 2 may not be due to the siRNA targeting Gene A, Explain why she might be correct

Explanation / Answer

Ans-A- the gene A as shown is responsible for the contractions of the muscle cells so they it will be responsible for the various diseases associated with hyper contraction of Hart muscle cells.

Ans-B- the gene b is responsible for the relaxation of the muscle cells. it must be related with the various diseases arise due to a long relaxation of heart muscle cells.

Ans-C- the gene c will be concluded as the gene responsible for anxiety due to which hypertension arise.

An

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