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1a. When an acid reacts with an amine, the ____ is the nucleophile and the produ

ID: 976080 • Letter: 1

Question

1a. When an acid reacts with an amine, the ____ is the nucleophile and the product is a ____.

acid

amine

ester

amide

nitrile

1b. In an acid, ester, and nitrile, the carbonyl carbon and nitrile carbon behave like a ___. An amide is prepared by reacting ____.

nucleophile

electrophile

nitrile + LiAlH4

ester + NH3

amine + acid

1c. Ethyl acetate is converted to acetyl chloride by:

SOCl2

H3O+ followed by SOCl2

LiAlH4 followed by SOCl2

1d. Which method will convert acetic acid to acetonitrile? (check all that work)

oxidation followed by CN- substitution

reduction followed by HCN

NH3 followed by SOCl2

Explanation / Answer

1a) The amine is the nucleophile and the product is an amide

1b) behaves like a electrophile. An amide is prepared by reacting ester + NH3

1c) H3O+ followed by SOCl2

1d) reduction followed by HCN

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