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Use the following diagram from a Nature Review article that outlines +RNA viral

ID: 97416 • Letter: U

Question

Use the following diagram from a Nature Review article that outlines +RNA viral replication to help you answer the activity questions on the next page.

5. What viral process is happening part C and what enzyme does this?

Receptor binding Pro-apoptotic Anti-apoptotic effects effects Entry Shut off host cell (cap- dependent) translation Shut off host cell transcription Polyprotein st Interactions between the virus and the cell cycle Uncoating Viral replication complex Negative strand synthesis 5 dsRNA (latency?) IRES-driven translation strand (genome) 5 3 3' 3' 3 5 Packaging Cell lysis Viral egress

Explanation / Answer

Answer:

What viral process is happening part C and what enzyme does this?

This picture represents the Picornavirus replication (example Polio virus also belongs to Picornaviridae family of viruses).

The two positive RNA strands replicate and converts into a negative strand to synthesize more copies from it.The mRNA of this virus encodes RNA dependent RNA polymerase enzyme that makes complementary minus strands of RNA. These complementary minus strands are then used as templates for the synthesis of more plus strands.

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