1.A nucleotide deletion in DNA replication a)causes all of the amino acids of th
ID: 96748 • Letter: 1
Question
1.A nucleotide deletion in DNA replication
a)causes all of the amino acids of the protein to be incorrect.
b)results in a change in the codons in mRNA from the point of the deletion onward, changing the sequence of amino acids inserted into the protein.
c)results in a change in a single codon at the point of the deletion, changing one amino acid in the sequence of the protein.
d)has no effect on the resulting protein
2. Based on the gene, mRNA and protein sequences that follow, what type of mutation-polypeptide effect has occurred?
Normal gene: TAC GCC GGC CCG AAA TTT ACT
mRNA: AUG CGG CCG GGC UUU AAA UGA
Normal protein: Methionine-Arginine-Proline-Glycine-Phenylalanine-Lysine
Mutated gene: TAC GCC GGC CCG ATA TTT ACT
mRNA: AUG CGG CCG GGC UAU AAA UGA
Protein: Methionine-Arginine-Proline-Glycine-Tyrosine-Lysine
a)base addition: change in one amino acid
b)base substitution: no change
c)base substitution: change in one amino acid
e)base deletion: change in one amino acid
3. Based on the gene, mRNA and protein sequences that follow, what type of mutation-polypeptide effect has occurred?
Normal gene: TAC GCC GGC CCG AAA TTT ACT
mRNA: AUG CGG CCG GGC UUU AAA UGA
Normal protein: Methionine-Arginine-Proline-Glycine-Phenylalanine-Lysine
Mutated gene: TAC GCC GGT CCG AAA TTT ACT
mRNA: AUG CGG CCA GGC UUU AAA UGA
Protein: Methionine-Arginine-Proline-Glycine-Phenylanine-Lysine
a)deletion: silent or no change
b)substitution: change in one amino acid
c)substitution: silent or no change
Explanation / Answer
1) Amino acids are coded by a sequence of three nucleotide that constitute a codon. Each amino acid has a very distinctive and specific codons. So, in case of a nucleotide deletion during DNA replication causes frame shift mutation. This results in change in the codons in mRNA from point of deletion onwards changing the sequence of amino acid into the protein (option b).
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.