Base analog causes mutation by: A) inserts between paired bases B) competes with

Question

Base analog causes mutation by: A) inserts between paired bases B) competes with natural bases C) removes amino groups from bases D) cause strand break E) form thymine dmers Frameshift mutation causes: A) alteration of reading frame of entire protein from the point of mutation B) change of a codon to a stop codon acid C) change of a codon that will cause incorporation of same amino D) addition of one or more bases. E) deletion of one or more bases Study the nucleotide sequences of wild type and it's mutant gene below. This mutation can best be called: A) Non-sense B) Silent C) Frameshift D) Mis-sense E) All of the above

Explanation / Answer

a) base analog competes with natural bases and causes base pairing change in DNA.

eg- 2 amino purine, 5 bromo uracil.

b) frameshift mutation is caused by either insertion or deletion of bases from the DNA which alter the reading frame of the entire protein from the point of mutation. like in this case, in wild-type CCC codes for Proline amino acid and in mutated CCT is also codes for Proline amino acid.

c) this mutation is called silent mutation. in a silent mutation, base change takes place but this base change in codon code for the same amino acid as the wild type codon.

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