The three most common HPLC detectors used in the clinical laboratory are absorba

Question

The three most common HPLC detectors used in the clinical laboratory are absorbance, flurescence, and electrchemical detectors. What is the most important limitation of these detectors?

1. These detectors will not provide a linear relationship between detector output and concentration

2. These detectors will provide preliminary solute identification only

3. These detectors will provide semi-quantitative data only

4. These detectors lack the needed sensitivity to be useful in clinical laboratory analysis

Explanation / Answer

The most important limitation of these detectors is lack the needed sensitivity to be useful in clinical laboratory analysis

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