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50 POINTS QUESTION!! Tamiflu is an anti-influenza drug designed to reversibly bi

ID: 92878 • Letter: 5

Question

50 POINTS QUESTION!!

Tamiflu is an anti-influenza drug designed to reversibly bind to an enzyme, neuraminidase, on the influenza virus protein coat. To be a tight binder to the neuraminidase active site, what must Tamiflu mimic? The active site The transition state The product The substrate An enzyme has a K_M of 47 pM. If the V_max of the preparation is 22 mu mol. L^1. min^-1, what velocity would be observed in the presence of 10 mu M substrate and 4 mu M of an uncompetitive inhibitor that has a K_1 of 3 mu M.

Explanation / Answer

Answer 4)

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