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A cell can repair cytosine deamination damage, so it presumably has an enzyme th

ID: 92361 • Letter: A

Question

A cell can repair cytosine deamination damage, so it presumably has an enzyme that "recognizes" the product of this damage. The structural feature that this repair enzyme recognizes would most likely be:

A1. A bulge in the duplex caused by cytosine deamination replacing a pyrimidine with a purine.

A2. Non-planarity of the base, due to removal of the amine group.

A3. Free radicals created by the cytosine deamination reaction.

A4. C-rich sequences created by the cytosine deamination reaction.

A5. None of the above would be plausible features recognized.

Explanation / Answer

Cytosine deamination Process release ammonia and form Uracil.

ln this process Pyrimidine (C) is replaced by purine (U).

Due to this replacement a bulg appear in duplex.

option (A1) is correct for cell repair cytosine deamination damage.

( A bulge in the duplex caused by cytosine deamination replacing a pyrimidine with a purine)

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