Erythromycin (ERY) is an antibiotic that controls bacteria growth by acting as a

Question

Erythromycin (ERY) is an antibiotic that controls bacteria growth by acting as a protein synthesis inhibitor. Erythromycin binds to the ribosomal exit tunnel of bacterial ribosomes(see figure below). Which of the following statements is MOST LIKELY to be true? A The association between erythromycin and the ribosome takes place only when the ribosome is free from a growing peptide chain, and, when that growing peptide chain is covalently attached to a tRNA. B Erythromycin inhibits protein synthesis by binding to the 23S rRNA molecule in the 30S subunit of the bacterial ribosome blocking the exit of the growing peptide chain. C Erythromycin will inhibit the incorporation of phenylalanine into growing peptides by a cell- free ribosomal system prepared from Escherichia coli. D The association between erythromycin and the ribosome is reversible. E The ionized from of erythromycin is considerably more permeable (able to diffuse across the membrane) to cells.

Explanation / Answer

Answer. The following statements are true:-

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