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**************How do I do question #2? UPGMA Phylogenetic Tree Construction Work

ID: 91887 • Letter: #

Question

**************How do I do question #2?

UPGMA Phylogenetic Tree Construction Worksheet

Step 1: Find the pair with the smallest distance. C&D

Step 2: Join them in one group and draw those branches. DISTANCE 2 units

Step 3: Compute average distance between this group and all other taxa one-by-one and create new table with those values.

Step 4: Repeat Steps 1 to 3 using the new distance matrix.

Characters

A

B

C

D

E

F

G

A

-

B

12

-

C

8

7

-

D

37

26

2

-

E

17

41

35

30

-

F

28

21

5

11

19

-

G

42

16

15

32

46

10

-

1. Based on above data, find the first two characters with the shortest distance and draw those branches with the respective distances on the branches below according to the example given in class or online. This should be your first two branch tips.

2. Recalculate distances based on the combination of the last characters. This first table has been partially filled out for you. Determine and enter the missing values. (You need not fill out the boxes above the dashes as they are mirror values to the below-dash values.)

A

B

CD

E

F

G

A

-

B

12.00

-

CD

22.50

-

E

17.00

41.00

32.50

-

F

28.00

21.00

19.00

-

G

42.00

16.00

10.00

-

Characters

A

B

C

D

E

F

G

A

-

B

12

-

C

8

7

-

D

37

26

2

-

E

17

41

35

30

-

F

28

21

5

11

19

-

G

42

16

15

32

46

10

-

Explanation / Answer


A

B

CD

E

F

G

A

-

B

12.00

-

CD

22.50

16.50

-

E

17.00

41.00

32.50

-

F

28.00

21.00

8.00

19.00

-

G

42.00

16.00

23.50

46.00

10.00

-

These can be calculated by adding distance between the X group with C and with D and then dividing it with 2 in order to find distance between X group and CD.

Example, distance between B and CD = (7+26) / 2 = 16.50

Distance between F and CD = (5+11) / 2 = 8.00

Distance between E and G remains unchanged.


A

B

CD

E

F

G

A

-

B

12.00

-

CD

22.50

16.50

-

E

17.00

41.00

32.50

-

F

28.00

21.00

8.00

19.00

-

G

42.00

16.00

23.50

46.00

10.00

-