1A) Why is it possible for hormones, such as estrogen, to be delivered through a
ID: 90005 • Letter: 1
Question
1A) Why is it possible for hormones, such as estrogen, to be delivered through a patch attached to the skin while other hormones such as insulin have to be injected?1B) What are some possible problems associated with using the patch delivery system?
1C) Give another hormone and how you think it could be delivered. Hint: Think about what type of molecules can cross the cell membrane. 1A) Why is it possible for hormones, such as estrogen, to be delivered through a patch attached to the skin while other hormones such as insulin have to be injected?
1B) What are some possible problems associated with using the patch delivery system?
1C) Give another hormone and how you think it could be delivered. Hint: Think about what type of molecules can cross the cell membrane.
1B) What are some possible problems associated with using the patch delivery system?
1C) Give another hormone and how you think it could be delivered. Hint: Think about what type of molecules can cross the cell membrane. 1B) What are some possible problems associated with using the patch delivery system?
1C) Give another hormone and how you think it could be delivered. Hint: Think about what type of molecules can cross the cell membrane.
Explanation / Answer
1A.Estrogen patches contain the active ingredient estradiol hemihydrate which Is occuring naturally form of the oestrogen. And Is Lipid Soluble Can Cross Plasma Membrane Easily. While insulin is a large molecule and protenicious In Nature therefore is not usually absorbed by the skin.
B.Problem With Patch Delivery System
1.Poor diffusion of large molecules
2. Skin Irritation
3. Require High drug Load
4.Unsuitable If Drug dose is large.
5. Absorption Efficiency Is Different Of Different Site Of Skin
C.Other Harmone Is Progestin.
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