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The lactose permease of E. coli is a protein composed of a single polypeptide th

ID: 8904 • Letter: T

Question

The lactose permease of E. coli is a protein composed of a single polypeptide that is 417 amino acids in length. By convention, the amino acids within a polypeptide are numbered from the amino terminus to the carboxyl terminus. Are the following questions about the lactose permease true of false?

A. Since the sixty-fourth amino acid is glycine and the sixty-eighth amino acid is aspartic acid, the codon for glycine-64 is closer to the 3' end of the mRNA compared to the codon for aspartic acid-68.

B. The mRNA that encodes the lactose permease must be greater than 1,241 nucleotides in length.

Explanation / Answer

A) false - since the mRNA is processed in the 5' -> 3' direction, the later amino acid is closer to the 3' terminus. B) True - the mRNA must be at least 3 times the length of the number of amino acids (3 times 417 = 1251) Hope that helps! Jonathan

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