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Basic Bio, just Short answer like few words only, answer them all and i will rat

ID: 88555 • Letter: B

Question

Basic Bio, just Short answer like few words only, answer them all and i will rate you

1-What’s the difference in resolution between your eye and a typical laboratory compound light microscope? Between a light microscope and a TEM?

2-Light micrographs are obtained by directing photons through a specimen. In general, how are TEMs and SEMs obtained? What’s the fundamental difference in the images obtained from these two different types of microscopes?

3-In terms of quantity, 98% of a plasma membrane is lipid (most of which are phospholipids) and 2% is protein. However, 50% of the weight of a plasma membrane is lipid and 50% is protein. What does this latter fact say about proteins in the membrane?

4-How does cholesterol in the membrane affect membrane fluidity? If cholesterol is so important in maintaining the integrity of membranes, why is it often seen as bad for you?

5-What is the difference between and integral membrane protein and a peripheral membrane protein? How does a carrier protein differ from a channel protein? What are the 3 different ways in which channels are gated in the human body?

Explanation / Answer

1. Resolution of light microscope- 200 nm

Resolution of STEM - 50 pm

Resolution of human eye - 288 mm

2. In electron microscope, the specimens are bombarded by a high energy electron beam. These electron beams result in images that are black and white in colour in contrast to images obtained by light microscopes which are coloured, due to the visible light.

3. This indicates that the proteins present in the plasma membrane are of higher weight or higher kilo Dalton since even after being lesser in quantity, these weigh equal to the lipids present.

4. Cholesterol maintains membrane fluidity by acting as a bi directional regulator. It is responsible in maintaining the membrane stability at high temperatures by increasing the melting point and at low temperatures it regulates the phospholipids by not allowing them to form a cluster and stiffen. Cholesterol being so important turns out to be bad when it crosses its normal range. Anything above the normal range is bad, and so is cholesterol. A very high amount of LDL type cholesterol occurs because it results in the buildup of fatty acids in the arteries.

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