72. Which of the following combination of events are associated with activation

Question

72. Which of the following combination of events are associated with activation of the b-adrenergic receptor pathway?

I. Binding of an antagonis

II. Binding of an agonist.

III. Ligand-induced membrane spanning conformational changes.

IV. Ligand-induced conformational changes that occur only in extracellular region of the receptor.

V. An increased association between the receptor protein and G protein.
VI. An increased dissociation between the receptor protein and G protein.

VII. Association of multiple subunits to form a trimeric G protein.

VIII. Dissociation of the trimeric G protein
IX. Conversion of Ga(GDP) to Ga(GTP).
X. Conversion of Gb(GDP) to Gb(GTP).

A. I, III, VI, VIII, & IX

B. II, III, VI, VIII, & IX

C. II, IV, VI, VIII, & IX

D. II, III, VI, VIII, & X
E. II, III, V, VII, & XI

Explanation / Answer

Pathway

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