Use this partial DNA sequence (the original sequence with no mutations) to answe

Question

Use this partial DNA sequence (the original sequence with no mutations) to answer the following questions.

5' - C A A - 3'
3' - G T T - 5'

Part C

Suppose that the top strand is the coding (nontemplate) strand and the three bases shown represent a single in frame codon in a gene.

What will be the effect of the tautomeric shift-induced mutation on the amino acid sequence?

-nonsense mutation -silent mutation -missense mutation -not enough information to determine Hac HAH N' ..H -N G CH, Rare tautomer H2C N-H OT 5 CH2 H Rare tautomer Or 3 O H2C H H OH Rare tautomer H2C. "H-N A. o s HC H OH Rare tautomer Pearson Education, Inc.

Explanation / Answer

Tautomeric shift induced mutation will lead to C pairing with A. Ultimately this would result in the formation of a stop codon (UAA).

This won't code for any amino acid and thus is a case of non sense mutation.

Correct option is (a).

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