Use this pathway to answer questions 1-8. e3 ATP ADP P ATP ADP NADH NAD rede cti

Question

Use this pathway to answer questions 1-8. e3 ATP ADP P ATP ADP NADH NAD rede ction e7 eg eo 10 About this pathway: A-Z are substrates and/or products. eren are enzymes responsible for the metabolism of A-Z. Z is essential for cellular function. Overproduction of T results in a medical disorder. T has no regulatory effects on the pathway. 1. (3 poins) Identify the class of the enzymes below: 2. (4 poins) Identify the enzymes that would most likely be allosterically regulated via feedback. Sketch this regulation on the pathway above. Allosterically regulated enzymes:

Explanation / Answer

1.

E2 is a transferase. It is a kinase enzyme that transfers phosphate group from ATP to a substrate.

E4 is an oxidoreductase. It removes protons from the substrate and couples it with the conversion of NAD+ to NADH.

E6 is an ATPase as it catalyzes the hydrolysis of ATP to ADP+Pi.

2.

ADP is a product of the E2 reaction. So, ADP could be an allosteric inhibitor of E2 activity.

NADH is a product of the E4 reaction. So, NADH could be an allosteric inhibitor of E4 activity.

Z could serve as a feedback inhibitor of any of the initial reactions (A to B or M to N).

ADP could also be an inhibitor of E6.

E2 and E6 are activated by ATP.

E4 is activated by NAD+.

Related Questions

Navigate

• Browse (All)
• Browse U
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.