4) When keton bodies are made and where is it used? A) Keton bodies are made in

Question

4) When keton bodies are made and where is it used?

A) Keton bodies are made in the liver and used in adipose tissue to synthesize fatty acids

B) Keton bodies are made in the adipose tissue and used in the liver.

C) Keton bodies are made in muscle and used in the brain.

D) Keton bodies are made in the liver and used in brain.

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5) Secretion of insulin is

A) Stimulated by glucagon and inhibited by high glucose level in the blood.

B) Stimulated by low glucose and epinephrine in the blood.

C) Stimulated by high glucose and epinephrine in the blood.

D) Stimulated by high glucose level in the blood and inhibited by epinephrine.

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6) How de novo synthesis of fatty acid happens in cytosol. Starting material, acetyl CoA, is in mitochondria. How does acety CoA move from mitochondrial matrix to cytosol?

A) Acetyl CoA crosses mitochondrial membrane for de novo synthesis of fatty acid in cytosol.

B) Mitochondrial membrane disintegrates to let acetyl CoA to cross membrane for de novo synthesis of fatty acid.

C) Acetyl CoA reacts with OAA and citrate is formed. Citrate can move out of mitochondria to cytosol and form acetyl CoA again.

D) Malonyl CoA is synthesized from acetyl CoA in mitochondria, and malonyl CoA is used for the rest of de novo synthesis of fatty acid.

Explanation / Answer

4) Answer is D)Keton bodies are made in the liver and used in brain.

Ketone bodies are water soluble molecules produced by liver from fatty acids at the time of starvation. THey are used as source of energy for heart and brain. 5) Answer is C) Stimulated by high glucose and epinephrine in the blood.

When there is high level of glucose in the body secretion of insulin is mediated to lower its level. Epinephrine stimulates insulin release by activation of beta-adrenergic receptors.

6) Answer is C) Acetyl CoA reacts with OAA and citrate is formed. Citrate can move out of mitochondria to cytosol and form acetyl CoA again.

Acetyl CoA is formed in mitochondria from pyruvate combines with oxaloacetic acid to form citrate which is then transpoted to cytosol where it is again broken into acetyl CoA and OAA. OAA is reduced to malate which is transported to mitochondria and take part in citric acid cycle.

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