Antiviral drugs may target the following except A. uncoating. B. nucleic acid sy

Question

Antiviral drugs may target the following except A. uncoating. B. nucleic acid synthesis. C. viral assembly. D. viral ribosomes. E. uncoating, nucleic acid synthesis AND viral assembly. The process used for identifying the different carbohydrates of streptococci is called A. Lancefield grouping. B. CHO typing. C. streptococci. D. fermentation testing. The cause of strep throat is A. Staphylococcus aureus B. Streptococcus pyogenes-beta-hemolytic, group A C. Staphylococcus pyogenes- alpha-hemolytic, group B D. Streptococcus pneumoniae Virulence factors used by S pyogenes may be A Protein F. B. M Protein. C. a capsule. D. Protein G. E. All of the choices are correct. The most common bacterial pathogen(s) involved with sinusitis, otitis media and conjunctivitis is/are A. S. aureus B. H. influenzae C. S. pneumoniae D. S. epidermidis E. H. influenzae AND S. pneumoniae Most common cold infections are probably caused by A. rhinovirus. B. S. aureus. C. Pseudomonas sp. D. E coli. A vaccine for the common cold is not feasible because A. the surface antigens of rhinovirus mutate frequently. B. the cause is unknown. C. the rhinovirus cannot be grown in sufficient quantities. D. there are more than 100 types of rhinovirus.

Explanation / Answer

1. D Viral ribosomes : Upto now there is no evidence of using ribosomes have drug targets, because viruses dont have any ribosomes it uses the host ribosomal machinery for viral protein synthesis, the Viral DNA integrated into the host DNA and regulate the host metabolism and makes viruses replicate, assembly, coating, so by the targeting the uncoating genes, assembly, protease inhibitors for avoiding maturation, blocking nucelic acid synthesis the viral forms can be targetted. Recently work undergoes on RNAprotein which encodes for ribosomes formation to treat Rabies virus but not yet approved.

2. A Lancifield grouping

This type used to check carbohydrates composition in the cell surface antigens used to group catalase negative, coagulase negative on their cell walls.

3. B Streptococcus pyogenes Group A beta hemolysins, (GAS) These are normally called Streptococcus pharyngitis causes infection at the area of the tonsils and pharynx, these produces two types of the exotoxins by the enzyme streptolysin which causes complete degradation of the RBCs results in the transparent yellow colored spots.Streptolysis O SLO get interacted with the cholestrol layer of the eukarytic blood cells which leads to the lysis.

4. E all of the above , Protein F (fibro nectin protein), M protein, a capsule (hyaluronic acid capsule inhibit the phagocytosis) and Protein G any of the above virulence factors of the S pyogenes

5. E haemophilus influenza and S.pneumoniae are the abcterial pathogens causes sinusitis, otitis media and conjuctivitis mostly seen in neonates.

6. A Rhino viruses, which is corona virus which probably called acute rhino pharyngitis or acute coryza, irritation and upper respiratory tract discomfort commonly called as cold with dry throat, running nose,blocked nose, sneezes, cough associated symptoms.

7.D there are more than 100 types of rhino strains are registered. So in a season more number of strains are frequently encountered based on our immune memory we acquire cold

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