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Some so-called \"7TM\" receptors use cAMP as second messenger, others use second

ID: 852493 • Letter: S

Question

Some so-called "7TM" receptors use cAMP as second messenger, others use second messengers derived from PIP2 (that is, from phosphatidylinositol 4,5-bisphosphate). Which of the following is true about the signaling pathway that uses second messengers derived from PIP2?

A. Hydrolysis of PIP2 generates just one second messenger, namely inositiol-triphosphate. B. A second messenger obtained from PIP2 hydrolysis remains within the lipid bilayer. C. IP3 activates protein kinase C. D. Diaylglycerol interacts with a channel or pore protein, causing calcium to flow from the endoplasmic reticulum into the cytosol.

Explanation / Answer

. Diaylglycerol interacts with a channel or pore protein, causing calcium to flow from the endoplasmic reticulum into the cytosol.

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