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Glucose is pumped into some animal cells by a symporter powered by the simultane

ID: 84286 • Letter: G

Question

Glucose is pumped into some animal cells by a symporter powered by the simultaneous entry of Na^+. The entry of Na^+ provides a free-energy input of 10.8 kJ/mol under typical cellular conditions (external [Na^+] = 143 M, internal [Na^+] = 14 mM, and membrane potential = -50 mV). How large a concentration of glucose can be generated by this free-energy input? Draw the structure of a 16 carbon fatty acid as 1) saturated, 2) trans monounsaturated, and 3) cis monounsaturated. Rank them in order of melting temperature.

Explanation / Answer

G = Na+negative

G = glucosepositive

T=37degreesC


The formula is:

G=RT Ln [Na+]In / [Na+]out+ZF

where G=10.8kL/mol

R= 8.314 J*K-1*mol-1

T= 37+ 273 = 310 k

[Na+]in =14mM

[Na+]out= 143mM

Z = ionic charge = -1

F= Faradays constant ( 96485JV-1mol-1

Phi = -0.05V (50 mV)

Putting those values in the equation:

You will get

0.05*96.485 - 8.314*0.309*ln(14/143))/(8.314*0.309)) = 66.7

So the concentration of glucose inside is 66 times more than outside.

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