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A 2-year-old male who missed several scheduled immunizations presents to the eme

ID: 83074 • Letter: A

Question

A 2-year-old male who missed several scheduled immunizations presents to the emergency room with a high fever, irritability, and a stiff neck. Fluid from a spinal tap reveals 20,000 white blood cells per milliliter with 85% polymorphonuclear cells. Gram stain evaluation of the fluid reveals small pleomorphic gram negative rods that grow on chocolate agar. If an inhibitor is designed to block its major virulence, which of the following would be the most likely major virulence factor? A. lgA protease synthesis B. Flagella synthesis C. Capsule formation D. Endotoxin assembly E. Exotoxin liberator

Explanation / Answer

A 2 year old male is suffered from pertusis caused by the bacterium bordetella pertusis . B. Pertusis is a small, obligately aerobic, gram negative coccobacillus. The virulent strain posses a capsule.

Your option C is correct that is capsule formation.

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