A new potential heart medicine, code-named X-281, is being tested by a pharmaceu
ID: 825509 • Letter: A
Question
A new potential heart medicine, code-named X-281, is being tested by a pharmaceutical company, Pharma-pill. As a research technician at Pharma-pill, you are told that X-281 is a monoprotic weak acid, but because of security concerns, the actual chemical formula must remain top secret. The company is interested in the drug's K_a value because only the dissociated form of the chemical is active in preventing cholesterol buildup in arteries.
To find the pKa of X-281, you prepare a 0.086 M test solution of X-281. The pH of the solution is determined to be 2.70. What is the pKa of X-281?
Express your answer numerically.
Explanation / Answer
[H+]= 2 x 10^-3 M
Ka = (2.00 x 10^-3)^2/ 0.093 - 2.00 x 10^-3 = 4.4 x 10^-5
pKa = 4.35
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