Mark ALL appropriate answers You immunize a rabbit with DNP-BSA in order to make

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Mark ALL appropriate answers

You immunize a rabbit with DNP-BSA in order to make anti-DNP IgG. While giving a booster shot 3 weeks late, you spill your DNP-BSA as the rabbit kicks you. The chemist who makes the DNP conjugate is on vacation but you do have some DNP-OVA.

You immunize a rabbit with DNP-BSA in order to make anti-DNP IgG. While giving a booster shot 3 weeks later, you spill your DNP-BSA as the rabbit kicks you. The chemist who makes the DNP conjugates is on vacation, but you do have some DNP-OVA. In order to induce a secondary immune response to DNP, your ONE BEST option is a. administer anti-DNP ab (passive transfer of immunity) prior to challenge with DNP-OVA. boost with DNP every week. immunize with OVA and wait 11/2 weeks before sensitization with DNP-OVA start all over: immunize with DNP-OVA and wait 3 weeks before boosting with DNP-OVA use passive transfer of anti-OVA ab as you challenge with DNP-OVA. inject PBL (peripheral blood lymphocytes) from a syngeneic rabbit sensitized with OVA (you happen to have this ready, fortunately) (adoptive transfer of immunity) at the same time that you inject DNP-OVA 1 week before injecting DNP-OVA, transfer CD8 T cells from a syngeneic rabbit sensitized with OVA none of the above; give up. None of this will work because of the carrier effect; you have to stick to DNP-BSA. In the above immunization, B cells must recognize DNP, while CD8+ T cells recognize BSA or OVA B cells must recognize BSA and OVA, while CD8+ T cells recognize DNP B cells must recognize DNP, while CD4+ T cells recognize BSA or OVA B cells must recognize BSA and OVA, while CD4+ T cells recognize DNP macrophages must recognize DNP, BSA and OVA all of the above none of the above In your generation of an antibody response as a result of a bacterial infection macrophages must present 'T cell determinants' to T_H cells on MHC II B cells must present the same (as above) 'T cell determinants' to the same (as above) T_H cells on MHC II. macrophages must present IL-1 to the very same T_H cells above T_H cells recognizing 'T cell determinants' MUST proliferate. T_H cells recognizing 'T cell determinants' MUST present IL-2 to antigen presenting B cells ALL of the above MUST take place. NONE of the above is essential, just useful.

Explanation / Answer

2. I will inject PBL from syngenetic rabbit sensitized with OVA at the same time that I inject DNP-OVA

3. B-cell must recognize DNP, while CD4+ T cells recognize BSA or OVA

4. B cell must present T cell determinant to TH cells on MHC II

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