Which of the following cellular compartments are NOT considered to be topologica

Question

Which of the following cellular compartments are NOT considered to be topologically equivalent? Nucleoplasm and cytosol. Cytosol and lumen of the endoplasmic reticulum. The space between the two nuclear membranes (inter-leaflet space) and the lumen of the ER. Lumen of the endosome and the extracellular space. Nuclear pores control the molecular traffic between the cytoplasm and nucleoplasm. Which statement about sorting into and out of the nucleus is INCORRECT? Large proteins can pass through nuclear pores if they have a signal patch usually comprising a Lys-rich domain. Ran GTPase enables transmembrane transport of proteins across the nuclear membranes. Small molecules (

Explanation / Answer

1. option D is correct. Nucleoplasm and cytosol have equivalent toplogy infact during mitosis the nuclear content mix with the cytosol. Also the endoplasmic reticulum is continuous with the interenuclear membrane space. The topology of cytosol and lumen of endoplasmic reticulum is also same.

2. Option A is correct. Signal patch with lysine (positively charged aminoacids) rich domain is presence is required nucleoprotein (the protein present in nuclear pore complex) not in the protein which has to be transported.

3. Option C is correct. Transport across the mitochondrial membrane involves TOM complex which translocate the subtance into the matrix of mitochondria through successive translocator complexes.

Related Questions

Navigate

• Browse (All)
• Browse W
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.