16–29 From Table 16–29 below, match the autoimmune disease in column A with the
ID: 81020 • Letter: 1
Question
16–29 From Table 16–29 below, match the autoimmune disease in column A with the corresponding antigen in column B and the consequence in column C. Use each answer only once. Then indicate whether the autoimmune disease is categorized as type II, III, or IV.
Table Q16–29
Column A
Column B
Column C
a. Rheumatoid arthritis
1. Myelin basic protein, proteolipid protein
A. Destruction of red blood cells by complement and phagocytosis, anemia
2. DNA, histones, ribosomes, snRNP, scRNP
B. Joint inflammation and destruction
c. Autoimmune hemolytic anemia
3. Thyroid-stimulating hormone receptor
C. Pancreatic cell destruction
4. Bacterial antigen
D. Glomerulonephritis
e. Multiple sclerosis
5. Rheumatoid factor IgG complexes
E. Hyperthyroidism
f. Systemic lupus erythematosus
6. Epidermal cadherin
F. Blistering of skin
g. Type 1 diabetes
7. Synovial joint antigen
G. Glomerulonephritis, vasculitis, arthritis
h. Graves’ disease
8. Rh blood group antigens
H. Systemic vasculitis
i. Pemphigus vulgaris
9. Pancreatic cell antigen
I. Brain degeneration, paralysis
Table Q16–29
Column A
Column B
Column C
a. Rheumatoid arthritis
1. Myelin basic protein, proteolipid protein
A. Destruction of red blood cells by complement and phagocytosis, anemia
2. DNA, histones, ribosomes, snRNP, scRNP
B. Joint inflammation and destruction
c. Autoimmune hemolytic anemia
3. Thyroid-stimulating hormone receptor
C. Pancreatic cell destruction
4. Bacterial antigen
D. Glomerulonephritis
e. Multiple sclerosis
5. Rheumatoid factor IgG complexes
E. Hyperthyroidism
f. Systemic lupus erythematosus
6. Epidermal cadherin
F. Blistering of skin
g. Type 1 diabetes
7. Synovial joint antigen
G. Glomerulonephritis, vasculitis, arthritis
h. Graves’ disease
8. Rh blood group antigens
H. Systemic vasculitis
i. Pemphigus vulgaris
9. Pancreatic cell antigen
I. Brain degeneration, paralysis
Explanation / Answer
Type II - Antibody against cell-surface or matrix antigen
Type III - Immune complex disease
Type IV - T-cell mediated disease
Column A -autoimmune disease Column B -corresponding antigen Column C - consequence Type of autoimmune disease a. Rheumatoid arthritis 7. Synovial joint antigen B. Joint inflammation and destruction Type IV Mixed essential cryoglobulinemia 5. Rheumatoid factor IgG complexes H. Systemic vasculitis Type III c. Autoimmune hemolytic anemia 8. Rh blood group antigens A. Destruction of red blood cells by complement and phagocytosis, anemia Type II Subacute bacterial endocarditis 4. Bacterial antigen D. Glomerulonephritis Type III e. Multiple sclerosis 1. Myelin basic protein, proteolipid protein I. Brain degeneration, paralysis Type IV f. Systemic lupus erythematosus 2. DNA, histones, ribosomes, snRNP, scRNP G. Glomerulonephritis, vasculitis, arthritis Type III g. Type 1 diabetes 9. Pancreatic cell antigen C. Pancreatic cell destruction Type IV h. Graves’ disease 3. Thyroid-stimulating hormone receptor E. Hyperthyroidism Type II i. Pemphigus vulgaris 6. Epidermal cadherin F. Blistering of skin Type IIRelated Questions
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