9. Test if the allele frequencies in our population are significantly different

Question

9. Test if the allele frequencies in our population are significantly different from the world-wide frequencies using a chi-square test.

Select one:

a. chi-square = 131.44; 1 degree of freedom, our population's allele frequencies are significantly different from the world-wide estimates

b. chi-square = 1.314; 1 degree of freedom, our population's allele frequencies are not significantly different from the world-wide estimates

c. chi-square = 1.314; 2 degrees of freedom, our population's allele frequencies are not significantly different from the world-wide estimates

d. chi-square = 131.44; 2 degrees of freedom, our population's allele frequencies are significantly different from the world-wide estimates

10. Use a chi-square independence test to determine if the genotypic frequencies differ between the tolerant and intolerant individuals. The chi-square value is:

Explanation / Answer

9)answer-b) Chi-square value=1.314 with 1 degree of freedom with values of freedom 8 according to the chi-square table with 99% confidence limit and p value=0.995. The population allele frequencies are not significantly different from the world- wide estimates.

The population survey was done for cytochrome enzyme gene cyp with single nucleotide polymorphism in different forms in different organs.

10)The chi-square analysis can be done to determine the tolerant and intolerant individuals with the expected values and the observed values as given in the experimental study with PCR analysis of single nucleotide polymorphism, RFLP analysis of genome sequences for a given tolerant and intolerant gene.

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