Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

1. The amino acid sequence shown below represents a portion of a peptide obtaine

ID: 80044 • Letter: 1

Question

1.            The amino acid sequence shown below represents a portion of a peptide obtained from a large protein.

1          2        3        4          5        6         7        8         9         10       11        12       13      14      15       16       17       18

Leu---His---Ile---Thr---Arg---Phe---Phe---Pro---Cys---Met---Gly---Glu---Ala---Ile---Pro---His---Thr---Glu-

   19       20      21       22        23     24      25       26      27       28      29      30      31        32

--Asp---Cys---Gln---Met---Ile---His---Cys---Pro---Arg---Lys---Gln---Pro---Tyr---Leu---

Where in this sequence would you find cross linked disulfide bonds?

Explanation / Answer

Cysteine,Methionine, homocystine and Taurine are sulfue containing amino acids.

SO the disulfide bonds would be formed between Cys-Met at position 9 & 10 and Met and Cys at position 22 & 25