Which process is conducted by mature naive B-cells to express both IgM and IgD a

Question

Which process is conducted by mature naive B-cells to express both IgM and IgD at the same time on their plasm membranes that bind specifically to the same antigen? a. Splicing the DNA genes for heavy chains and light chains b. Alternative splicing of the primary transcript to produce either mRNA with a mu constant segment of mRNA with a delta constant segment c. Modification of the polypeptide chains for IgM or by splicing them at different sites to form IgD d. two separate genes, one for IgM and one for IgD, are expressed in the same B cell e. Allelic exclusion produces the two different isotypes of B cell receptors The isotype class of antibodies is determined by the amino acid sequence in which part of the antibody molecule? a. The variable region of the heavy chains b. The constant region of the heavy chains d. The variable region of the light chains. e. The constant region of the light chains. The antigen binding sites is determined by the amino acid sequence in which part of the antibody molecule? a. The variable region of the light chains b. The constant region of the light chains c. The combined variable regions of one light chain and one heavy chains d. The variable region of the heavy chains e. The constant region of the heavy chains In order to develop into a plasma cell, a B-cell must receive "Signal 2" from which of the following? a. a dendrite cell b. an activated CDS T-cell c. an activated T_FH cell d. a macrophage e. a follicular dendrite cell Which DNA gene is rearranged first in developing T-cells? During specific recognition of antigen by t cells, which of the following allows them to focus their release of effector molecules on the the target cell without affecting adjacent cells? a. The formation of an immunological synapses that results from the target cell without affecting adjacent cells? a. The formation of an immunological synapsis that results from the polarization of T cell cytoplasmic structures b. The target cells have specific membrane receptors for the T cell molecules b. The target cells express fast receptors d. The T cell F as Ligand induces apotheosis in the target cells only e. All of the above answers are correct Naive CD 4 T cells will differentiable into which type of cell while other cells such as B cells, eosinophils, must cells, or basophils are secreting IL-4 in the same location where dendritic cells are activating the CD 4 T cells that bind their TCR to the peptide antigen presented on the dendritic cell's MHC class II? Why is it that armed effector CD8 cytoloxic T lymphocytes that were activated by APC presenting small pox, viral antigen are able to specifically recognize and kill cells infected with small pox virus but will not bind adjacent uninfected cells or those cells infected with Herpes virus? a. Only tissue cells that present small pox antigen on their MicA and MicB are recognized b. Only tissue cells that have less than normal expression of self antigen peptide on self MHC class 1 can be attacked c. Only tissue cells that present small pox virus peptides on their surface MHC class I class be recognized.

Explanation / Answer

86 - B

87 - B

88 - C

89 - C

90 - A

91 - E

92 - B

93 -C

94 - I could not go through all the choices. Please clarify them.

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