Using your knowledge or the material covered in Weeks 1-12, your general knowled
ID: 79443 • Letter: U
Question
Using your knowledge or the material covered in Weeks 1-12, your general knowledge of organic chemistry I, your textbooks and the Internet to answer the following questions regarding the DNA molecule. Label and give the name for the major functional groups in the DNA molecule? Functional groups are sites where chemical reactions take place. Using your knowledge of basic organic reactions, think about some possible reactions (e.g. SN2, E1, E2, SN1, etc.) that can occur at each of the functional groups in the DNA molecule? Label the functional groups in the DNA molecule as hydrophobic or hydrophilic? Is the overall DNA molecule generally classified as hydrophobic or hydrophilic? Explain your prediction. Discuss the type of bonding (e.g. ionic, covalent, coordinate covalent, hydrogen bonding, polar Covalent, non-polar covalent, etc.) at each functional group within the DNA moleculeExplanation / Answer
a. groups of molecules which are attached to organic molecules giving them particular characteristics or functions are called as Functional groups.
The DNA has the following functional groups are the amine, glycoside linkage, hydroxyl, amide, and phosphodiester
c. The sugar-phosphate backbone of DNA is a water loving polar part so it is hydrophilic; The internal part of DNA, that is the bases, are comparatively non-polar and therefore they are hydrophobic.
d. The bonding involved in between pyrimidines and purines is hydrogen bonding and between adjacent DNA bases is phosphodiester bonds
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