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A new potential heart medicine, code-named X-281, is being tested by a pharmaceu

ID: 765026 • Letter: A

Question

A new potential heart medicine, code-named X-281, is being tested by a pharmaceutical company, Pharma-pill. As a research technician at Pharma-pill, you are told that X-281 is a monoprotic weak acid, but because of security concerns, the actual chemical formula must remain top secret. The company is interested in the drug's K_a value because only the dissociated form of the chemical is active in preventing cholesterol buildup in arteries. To find the { m p}K_{ m a} of X-281, you prepare a 0.093it M test solution of X-281. The pH of the solution is determined to be 2.70. What is the { m p}K_{ m a} of X-281?

Explanation / Answer

HA -----> H+ + A- 0.093-x x x Ka = [H+][A-]/[HA] given [H+] = 10^-2.7 = 0.019953 = [A-] = x [HA] = 0.093-0.019953 = 0.091005 Ka = (0.019953^2)/(0.091005) = 0.004374 = 4.374 x10^ -3

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