Given below are the genotypic frequencies for a single gene with two alleles for

Question

Given below are the genotypic frequencies for a single gene with two alleles for three different populations:

AA Aa aa

Population 1 0.25 0.50 0.25

Population 2 0.35 0.56 0.09

Population 3 0.49 0.42 0.09

Which of the following is NOT a correct statement about these three populations?

A) Only two of the populations are in Hardy-Weinberg equilibrium
B) Population 1 is in Hardy-Weinberg equilibrium; the frequency of allele A is 0.5
C) Population 2 is not in Hardy-Weinberg equilibrium; the frequency of allele a is 0.37
D) Population 3 is in Hardy-Weinberg equilibrium; the frequency of allele A is 0.7
E) Population 3 is in Hardy-Weinberg equilibrium; the frequency of allele a is 0.3

Explanation / Answer

C) Population 2 is not in Hardy-Weinberg equilibrium; the frequency of allele a is 0.37 ----------. FALSE

Hardy and Weinberg described all the possible genotypes for a gene with two alleles. The binomial expansion representing this is, p2+ 2pq + q2= 1.0

Where,

p2 = proportion of homozygous dominant individuals

q2 = proportion of homozygous recessive individuals

2pq = proportion of heterozygotes.

In case of population 2, the frequency of AA or p2 = 0.35, p = 0.59.

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