Why do we see geographical differences in the occurrence of cancer? What are the

Question

Why do we see geographical differences in the occurrence of cancer? What are the current treatments for cancer? How do you distinguish normal and neoplastic tissue Describe the abnormality which leads to chronic myelogenous leukemia (CML)? Describe the mechanism of action of Gleevec What are the possible cancer treatments that are in the experimental stage ? How can we use virus to kill a cancer cells? What is angiogenesis? How is engineered anaerobic bacteria used to treat cancer? Can cancer patient be treated with a single therapy? Can we use hormone therapy to treat cancer? Can a person get multiple cancers?

Explanation / Answer

11. Geographical differences are there in the occurrence of cancer. This may be due to the difference in environmental conditions, exposure to different variety of pollutants, variances in susceptibility to mutations based on their gene pool, differences in food habits and life styles, etc.

12. The current treatments available for cancer include,

a. Chemotherapy (by using cytotoxic drugs)

b. Radiation therapy (using X-rays, gamma rays and charged particles)

c. Bone marrow transplantation (for certain cancers like blood cancer)

Therapeutic drug targeting is a new approach in pharmacotherapy particularly in the treatment of cancer. The drugs used in targeted therapy were designed to interfere with the specific molecular targets such as mutated genes, proteins, or other biological molecules that contribute to the survival and growth of tumor cells

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