In meiosis I the centromeres of a pair of [____] work in unison so that they fac
ID: 74765 • Letter: I
Question
In meiosis I the centromeres of a pair of [____] work in unison so that they face, and attach to, the same spindle pole. A(n) [____] containing the protein Rec8 (securin) holds the sister chromatids together at centromeres and along chromosome arms. [____] is triggered by cleavage by separase of cohesin and Rec8 of the chromosome arms, allowing the homologous pairs to disengage and move to opposite poles. However, a newly discovered protein, Sgo1, protects cohesin and Rec8 remaining at centromeres during anaphase I, so that the [____] remain tethered to each other. Sgo1 is degraded after anaphase I, so that at metaphase II centomeric cohesin and Rec8 are no longer protected from separase, and their cleavage at anaphase II allows [____] to separate.
(1) homologous chromosomes; APC; Anaphase; centromeres; sister chromatids
(2) chromatids; M-phase Cdk; Telophase; parental homologues; sister chromatids
(3) homologous chromosomes; APC; Anaphase II; parental chromosomes; sister chromatids
(4) sister chromatids; cohesin complex; Anaphase I; sister chromatids; sister chromatids
(5) sister chromatids; APC; Metaphase I; centromeres; parental homologues
Explanation / Answer
Correct answer is (4)
4)Ans : sister chromatids; cohesin complex; Anaphase I; sister chromatids; sister chromatids.
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