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Suppose a steroid animal hormone acts at the gene level to alter the behavior of

ID: 73101 • Letter: S

Question

Suppose a steroid animal hormone acts at the gene level to alter the behavior of a target cell; assume the alteration in cell behavior requires a cytoplasmic protein that was not present prior to interaction of the hormone with the target cell. Beginning with binding of the hormone to it to its receptor, summarize the steps leading to appearance of the final functional gene product. For each step, be sure to include the cellular compartment in which the step occurs and cellular components involved in each step.

Explanation / Answer

Steroid hormone binds to receptor in cytoplasm-----> After binding, the hormone-receptor complex moves into the nucleus-----> here it can bind with HRE (hormone response elements) in DNA----->This causes transcription at this site------->mRNA is produced-----> this mRNA moves into the cytoplasm------> causes protein synthesis and as a result, the required cytoplasmic protein (mentioned in the question) is produced ----->behaviour of target cell changed.

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