- Nernst equation Step 3: Fill out the first two columns of the chart below usin

Question

- Nernst equation Step 3: Fill out the first two columns of the chart below using the Nernst equation. Make sure to show your work! Equilibrium Simulation Potential Alteration Nernst Calculation No alteration to K* permeability [K louside 150 [K'linside 5 [K'loutside 100 [K'inside 100 K'louside (K1-side- Step 4: Simulate each manipulation using the Nernst/Goldman Simulator (https/ Make sure you are on the "Nernst @37"" tab and the Permeability Preset is on "Squid Axon". Does the simulation support, not support, or unable to verify your hypothesis? Step 5: Use the Nernst/Goldman Simulator to model how the alterations to ion concentrations affecet membrane potential. Nernst Equation: 61.5 out og in

Explanation / Answer

The Nernst calculations can be performed as shown below.

According to the given Nernst equation, Ex = 61.5/z * Log([X]out/[x]in)

For the entry 1, there is no alteration to the K+ permeability.

For the entry 2: z = 1 (since the charge on the ion = +1)

i.e. Ex = 61.5/1 * Log(150/5) = 90.843 (since Log(150/5) = Log 30 = 1.4771)

For the entry 3: z = 1 (since the charge on the ion = +1)

i.e. Ex = 61.5/1 * Log(100/100) = 0 (since Log(100/100) = Log 1 = 0)

For the entry 4: [K+]outside and [K+]inside are not given.

The simulation part belongs to the chemical engineering branch, which is not of our subject.

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