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6) Anti-cancer drugs such as Vincristine act by disrupting the formation of micr

ID: 71485 • Letter: 6

Question

6) Anti-cancer drugs such as Vincristine act by disrupting the formation of microtubules. What process would you expect to be affected in the rapidly dividing tumor cells

a. formation of cleavage furrow

b. separation of sister chromatids

c. disassembly of the nuclear membrane

d. formation of the sister chromatids.

e. formation of the nuclear membrane

12) The end of the G2 phase in the cell cycle is marked by

a. beginning of DNA synthesis

b. beginning of cytokinesis

c. degrardation of cyclin

d. formation of the active cyclin and cyclin dependent kinase

e. degradation of the cyclin dependent kinase

Explanation / Answer

6). Answer is "b" Seperation of sister chromatids is stoped due to lack of microtuble. Which prone the cell for apoptosis. It not only inhibiting cancerous cell but also intestinal epithelial and bone marrow cells.

12). Answer is "d " formation of the active cyclin and cyclin dependent kinase.

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