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Scenario: You are the laboratory manager of a rural, 25 bed hospital with an ave

ID: 713496 • Letter: S

Question

Scenario: You are the laboratory manager of a rural, 25 bed hospital with an average daily census of 21 patients. Based on your market proposal, you were successful in replacing your outdated chemistry analyzer (Analyzer A) with a new model (Analyzer B). Perform the following validation studies based on the following results: 1. Precision Stud Sample # Instrument A 11.6 12.6 15.4 13.0 14.4 11.9 13.0 16.3 15.0 12.6 13.8 12.8 13.2 13.0 12..5 10.9 12.8 11.9 14.0 14.7 12.9 13.4 12.5 13.1 15.5 14.7 12.1 11.6 12.9 13.5 Reference Method 11.8 12.5 15.4 13.8 14.6 12.3 13.0 15.9 15.1 12.5 13.8 12.8 13.1 13.1 12.7 11.0 12.6 11.9 14.2 15.1 12.8 13.4 12.6 13.4 15.4 14.8 12.4 11.5 13.2 13.6 10 12 15 16 18 19 20 21 23 24 25 26 27 28 29 30 Show all work for calculation of the F test. What do the results show you when comparing the new method to the old method? Explain in detail

Explanation / Answer

Answer:

ANOVA : Single Factor

SUMMARY

Groups

Count

Sum

Average

Variance

Instrument A

30

397.6

13.25333

1.630851

Reference Method

30

400.3

13.34333

1.559092

ANOVA

Source of Variation

SS

df

MS

F

P-value

F crit

Between Groups

0.1215

1

0.1215

0.076177

0.783528

4.006873

Within Groups

92.50833

58

1.594971

Total

92.62983

59

From above ANOVA table it is seen that p-value = 0.783528 > > 0.05. Hence Instrument A and reference method provides nearly same results. Hence two methods seems to be at par.

ANOVA : Single Factor

SUMMARY

Groups

Count

Sum

Average

Variance

Instrument A

30

397.6

13.25333

1.630851

Reference Method

30

400.3

13.34333

1.559092

ANOVA

Source of Variation

SS

df

MS

F

P-value

F crit

Between Groups

0.1215

1

0.1215

0.076177

0.783528

4.006873

Within Groups

92.50833

58

1.594971

Total

92.62983

59

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